E-mail conversation with Bills, NFL writer Vic Carucci for the Buffalo News:

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Bob Kravitz

(WTHR) — Bob Kravitz spoke with Vic Carucci who covers the Buffalo Bills and NFL for the Buffalo News.

KRAVITZ:

We’re hearing now that Josh Allen will be out a few weeks with an injury. Who will be the Bills’ starting quarterback this Sunday in Indianapolis, and what does Nathan Peterman or Derek Anderson bring to the table?

CARUCCI:

As of Monday, Sean McDermott wasn't ruling Josh Allen out of Sunday’s game, although multiple reports have him possibly out for a while.

The coach included Nathan Peterman as a possibility to start, despite his disastrous finish to the Houston game when he threw a pick-six to give the Texans the winning points and another interception to seal the loss. Media members asked McDermott Monday why Peterman, who has had a series of disastrous showings practically every time he has played since his rookie season last year, is still on the roster. But McDermott believed in him enough to make him the starter of the season-opener at Baltimore, even though Peterman performed poorly enough to be yanked early in the third quarter for Allen.

It’s hard to say exactly what 35-year-old Derek Anderson brings to the table beyond his 14 NFL seasons, most of which have been as a backup. Until last Wednesday, he hadn't practiced with an NFL team since January, when he was in the last of his seven seasons as Cam Newton’s mentor in Carolina. The Bills signed him to mentor Allen. Given how poorly Peterman performed last week, it’s hard to imagine putting him out there again. But if Allen is unable to go, Anderson might very well have to start if only by default.

KRAVITZ:

So what has to happen Sunday for the Bills to upset the Colts (yes, Vegas has Indy as a sizable favorite)?

CARUCCI:

Their defense must dominate as it did at Houston, putting every bit as much pressure on Andrew Luck as it did on Deshaun Watson. The offense must stay committed to the run and whoever plays quarterback must take exceptionally good care of the ball.

KRAVITZ:

OK, the pick. I don't like either team, honestly. But in the end, you've got to like the quarterback matchup – Andrew Luck against Derek Anderson. Look for a low-scoring game. Colts, 20-16.

CARUCCI:

Asking Derek Anderson to emerge from semi-retirement and give the Bills competent enough quarterbacking to pull out a road win is asking a lot, even against a bad opponent. Colts win this game, 27-17.

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